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Think and Do The Extraordinary

Julio Monti Belmonte

Assistant Professor

Riddick Hall 145


Dr. Belmonte joined NC State in August 2018 as a Chancellor’s Faculty Excellence Program cluster hire in Modeling the Living Embryo. He obtained his bachelor’s and master’s degrees in physics from Universidade Federal do Rio Grande do Sul in Brazil, where he developed a model for collective cell movements during tissue regeneration. During his Ph.D. in biophysics, under the supervision of James Glazier at Indiana University Bloomington, he developed new computational models for the description of epithelial cells and applied them to study a variety of biological processes such as somitogenesis, limb formation and cystogenesis. As a multidisciplinary postdoctoral fellow at the labs of Maria Leptin and François Nédélec at the European Molecular Biology Laboratory, he focused his research in the mechanisms of force production of cytoskeletal networks and their role in developmental processes.

Research Description

Dr. Belmonte research group aim is to understand the physical principles behind cell mechanics and how they give rise to force production and pattern formation. He uses computer simulations to study these processes at both the tissue level, looking at the formation of organs; and at the subcellular level, asking how active cytoskeletal structures generate the forces that ultimately shape all living things.  


Complete list of publications

Selected Publications

Cellular Mechanisms of Chick Limb Bud Morphogenesis
G Lesnicar-Pucko*, JM Belmonte*, M Musy, JA Glazier, JA Sharpe
BioRxiv, (2020), doi:10.1101/2020.09.10.292359

A Mechanical Model for Somite Segmentation
P Adhyapok, A Piatkowska, MJ Norman, SG Clendenon, CD Stern, JA Glazier, JM Belmonte
BioRxiv, (2020), doi:10.1101/804203

Parameterizing cell movement when the instantaneous cell migration velocity is ill-defined
GL Thomas, I Fortuna, GC Perrone, JA Glazier, JM Belmonte, RMC de Almeida
Physica A, 550, (2020), 124493

CompuCell3D Simulations Reproduce Mesenchymal Cell Migration on Flat Substrates
I Fortuna, G Perrone, MS Krug, E Susin, JM Belmonte, GL Thomas, JA Glazier, RMC de Almeida
Biophysical Journal, 118, (2020), 2801

Polarity sorting drives remodeling of actin-myosin networks
V Wollrab, JM Belmonte, L Baldauf, M Leptin, F Nedelec, GH Koenderink
Journal of Cell Science, 11, (2019), doi:10.1242/jcs.219717

A Disassembly-driven Mechanism Explains F-actin-mediated Chromosome Transport in Starfish Oocytes
P Bun, S Dmitrieff, JM Belmonte, FJ Nédélec, P Lénárt
eLife, (2018), 7:e31469

A Theory that Predicts Behaviors of Disordered Cytoskeletal Networks
JM Belmonte, M Leptin, F Nédélec
Molecular Systems Biology, (2017), 13:941

Filopodial-Tension Model of Convergent-Extension of Tissues
JM Belmonte, MH Swat, JA Glazier
PLoS Comput. Biol., (2016), 12: e1004952

Virtual-Tissue Computer Simulations Define Roles of Cell Adhesion and Proliferation in the Onset of Kidney Cystic Disease
JM Belmonte*, SG Clendenon*, GM Oliveira*, MH Swat, EV Greene, JA Glazier, RL Bacallao
Molecular Biology of the Cell, (2016), 27: 3673-3685

Somites Without a Clock
AS Dias, I de Almeida, JM Belmonte, JA Glazier, CD Stern
Science, (2014), 343: 791

Multi-scale Modeling of Tissues Using CompuCell3D
MH Swat, GL Thomas, JM Belmonte, A Shirinifard, D Hmeljak, JA Glazier
Methods in Cell Biology, (2012), 110: 325

Self-Propelled Particle Model for Cell-Sorting Phenomena
JM Belmonte, GL Thomas, LG Brunnet, RMC De Almeida, H Chaté
Phys. Rev. Lett., (2008), 100: 248702

Supervised Students

  • Elijah Numa