Julio Monti Belmonte
Dr. Belmonte joined NC State in August 2018 as a Chancellor’s Faculty Excellence Program cluster hire in Modeling the Living Embryo. He obtained his bachelor’s and master’s degrees in physics from Universidade Federal do Rio Grande do Sul in Brazil, where he developed a model for collective cell movements during tissue regeneration. During his Ph.D. in biophysics, under the supervision of James Glazier at Indiana University Bloomington, he developed new computational models for the description of epithelial cells and applied them to study a variety of biological processes such as somitogenesis, limb formation and cystogenesis. As a multidisciplinary postdoctoral fellow at the labs of Maria Leptin and François Nédélec at the European Molecular Biology Laboratory, he focused his research in the mechanisms of force production of cytoskeletal networks and their role in developmental processes.
Area(s) of Expertise
Dr. Belmonte research group aim is to understand the physical principles behind cell mechanics and how they give rise to force production and pattern formation. He uses computer simulations to study these processes at both the tissue level, looking at the formation of organs; and at the subcellular level, asking how active cytoskeletal structures generate the forces that ultimately shape all living things.
- A mechanical model of early somite segmentation , iScience (2021)
- Mechanical competition alters the cellular interpretation of an endogenous genetic program , Journal of Cell Biology (2021)
- Cellular mechanisms of chick limb bud morphogenesis , (2020)
- CompuCell3D Simulations Reproduce Mesenchymal Cell Migration on Flat Substrates , Biophysical Journal (2020)
- Mechanical competition alters the cellular interpretation of an endogenous genetic programme , (2020)
- Parameterizing cell movement when the instantaneous cell migration velocity is ill-defined , Physica A: Statistical Mechanics and its Applications (2020)
- Polarity sorting drives remodeling of actin-myosin networks , Journal of Cell Science (2019)
- A disassembly-driven mechanism explains F-actin-mediated chromosome transport in starfish oocytes , eLife (2018)
- Fibroblast state switching orchestrates dermal maturation and wound healing , Molecular Systems Biology (2018)
- A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self‐renewal , Molecular Systems Biology (2017)